AKTIVITAS FOTOPROTEKTIF IN VITRO SEDIAAN KRIM EKSTRAK HERBA PUTRI MALU (Mimosa pudica L.) SEBAGAI TABIR SURYA

Penulis

  • In Rahmi Fatria Fajar1 Program Studi Farmasi, Institut Sains dan Teknologi Al-Kamal
  • Dewi Rahma Fitri Program Studi Farmasi, Institut Sains dan Teknologi Al-Kamal
  • Yulis Adriana Program Studi Farmasi, Institut Sains dan Teknologi Al-Kamal
  • Handawati Silitonga Program Studi Farmasi, Institut Sains dan Teknologi Al-Kamal
  • Pra Panca Bayu Chandra Program Studi Farmasi, Sekolah Tinggi Ilmu Kesehatan IKIFA

Kata Kunci:

Mimosa pudica L., cosmetics, cream, sunscreen, SPF

Abstrak

The sensitive plant (Mimosa pudica L.) has great potential as a raw material for cosmetics due to its bioactive compounds that can neutralize free radicals. One of its applications is as a sunscreen agent that protects the skin from the harmful effects of the sun’s ultraviolet (UV) radiation. This study aims to determine the Sun Protection Factor (SPF) value of a 70% ethanol extract of the sensitive plant, formulate it into a cream, and evaluate the physical characteristics and sunscreen activity of the formulation. The in vitro SPF value was calculated using UV-Vis spectrophotometry based on the Mansur formula. The cream formulations were prepared in four variations with different extract concentrations: F0 (0%), F1 (0.3%), F2 (0.6%), and F3 (0.9%). Physical evaluation of the formulations included organoleptic testing, homogeneity, spreadability, pH, and viscosity. The results of the physical evaluation showed that all four formulations exhibited good homogeneity. The spreadability test yielded results that met the requirements (5–7 cm), and the pH test results fell within the safe range for the skin (4.5–6.5). The viscosity of the creams decreased as the concentration of the added extract increased. The SPF test results for the cream formulations showed the following values: F0 at 1.8810 (no protection), F1 at 14.2306 (maximum protection category), F2 at 27.2598 (ultra protection category), and F3 at 33.1475 (ultra protection category). Conclusion: A 70% ethanol extract of the putri malu herb was successfully formulated into a sunscreen cream that meets physical quality requirements, and increasing the extract concentration significantly enhanced its photoprotective activity, reaching the ultra protection category.

Referensi

1. Shovyana Hh, Zulkarnain Ak. Physical Stability And Activity Of Cream W / O Etanolik Fruit Extract Mahkota Dewa ( Phaleria Macrocarph ( Scheff .) Boerl ,) As A Sunscreen. Vol. 18. 2013. P. 109–17.

2. Wijaya Ir, Safitri C. Uji Aktivitas Formulasi Lip Balm Dari Ekstrak Bekatul Padi (Oryza Sativa) Sebagai Tabir Surya. Pros Snpbs (Seminar Nas Pendidik Biol Dan Saintek). 2020;5:276–83.

3. Lee S, Yu Js, Phung Hm, Lee Jg, Kim Kh, Kang Ks. Potential Anti-Skin Aging Effect Of (-)-Catechin Isolated From The Root Bark Of Ulmus Davidiana Var. Japonica In Tumor Necrosis Factor-Α-Stimulated Normal Human Dermal Fibroblasts. Antioxidants. 2020;9(10):1–13.

4. Mardhiah A, Surya E, Ervilita R. Skrining Fitokimia Tumbuhan Putri Malu ( Mimosa Pudica L ) Sebagai Obat Tradisional Masyarakat Aceh Phytochemical Screening Of The Mimosa Puddica L . Plant As A Traditional Medicine Of The Aceh Community. 2025;11(2):119–29.

5. Faturrahman, Titin, Reny Radita Putri, Anita Tri Andriani, Syarifah Zulfa Aripah Billah, Sayyida Nafisa V. Studi Literatur: Aktivitas Farmakologis Putri Malu (Mimosa Pudica L.). J Pendidik Biol. 2024;9(1).

6. Jannah Nt, Agustini Tw, Anggo D. Penerapan Ekstrak Putri Malu Sebagai Penghambat Melanosis Pada Udang Selama Penyimpanan Dingin. 2018;131–40.

7. Rahmi I, Fajar F, Fitri Dr, Fitriyani N, Chuanvin M. Comparison Of Antioxidant Activities Of Tespong Herbal ( Oenanthe Javanica Dc .) Extract And Nanoextract Using Dpph Method Perbandingan Aktivitas Antioksidan Ekstrak Dan Nanoekstrak Herba Tespong ( Oenanthe Javanica Dc .) Dengan Metode Dpph. 2021;17(1):1–8.

8. Dewi Rahma Fitri, In Rahmi Fatria Fajar Skn. Anti-Mosquito Lotion Formulation With 70 % Ethanol Extract Of Kawista Fruit As An Active Substance Program Studi Farmasi , Institus Sains Dan Teknologi Al-Kamal , Jl . Kedoya Raya No 2 , Jakarta Barat , 11520 , Indonesia Program Studi Teknik Industri , In. Sanitas J Teknol Dan Seni Kesehat. 2022;13(1):56–67.

9. Zakky M, Akbar P, Wijaya Sm, Carolia N, Sukohar A, Dokter P, Et Al. Pengaruh Ekstrak Buah Adas ( Foeniculum Vulgare ) Terhadap Pertumbuhan Bakteri Salmonella Typhi Secara In Vitro Effect Of Fennel Fruit Extract ( Foeniculum Vulgare ) On The Growth Of Salmonella Typhi Bacteria In Vitro. 2024;14:1635–9.

10. Nurrohim S, Harjanti R, Dewi Purnamasari Na. Formulasi Dan Evaluasi Serum Anti-Aging Hesperetin Dalam Sistem Nlc (Nanostructured Lipid Carriers) Dengan Metode Emulsifikasi-Sonikasi. Media Farm Indones. 2022;17(1):25–35.

11. Sugiharta S, Ningsih W. Evaluasi Stabilitas Sifat Fisika Kimia Sediaan Krim Ketoconazole Dengan Metode Stabilitas Penyimpanan Jangka Panjang. Maj Farmasetika. 2021;6(Suppl 1):162.

12. Ariani L, Miftahurrohmah Nur, Ang M. Formulasi Krim Minyak Biji Bunga Matahari ( Helianthus Annuus L .) Dengan Variasi Konsentrasi Setil Alkohol Sebagai Anti Jerawat ( Formulation Of Sunfl Ower Seeds Oil Cream ( Helianthus Annuus L .) With Variation Of Cetyl Alcohol Concentration As Anti Acn. 2020;18(2):235–40.

13. Wijaya Li, Safitri C. Uji Aktivitas Formulasi Lip Balm Dari Ekstrak Bekatul Padi (Oryza Sativa) Sebagai Tabir Surya. Pros Snpbs (Seminar Nas Pendidik Biol Dan Saintek). 2020;5:276–83.

14. Andayani Lh, Soulissa Ag, Tjandrawinata R. Edukasi Pemeliharaan Kesehatan Gigi Dan Mulut Pada Guru Dan Murid Sd Muhamadiyah 27 Jakarta Barat. :161–9.

15. Pine Atd, Alam G, Attamim F. Standardisasi Mutu Ekstrak Daun Gedi (. Pharm J Indones. 2017;

16. Hidayati Dn, Sumiarsih C, Mahmudah U. Standarisasi Non Spesifik Ekstrak Etanol Daun Dan Kulit Batang Berenuk (Crescentia Cujete Linn). J Ilm Cendekia Eksakta. 2018;1(19):19–23.

17. Inaku C, Aliah Ai, Farmasi Ps, Megarezki U, Raya Ja, Manggala K, Et Al. Jurnal Ilmiah Farmako Bahari Sunscreen Potential Preparations Cream Of Bitter Gourd Extract ( Momordica Charantia L .) Potensi Tabir Surya Formula Sediaan Krim Ekstrak Etanol Buah Pare ( Momordica Charantia L ). 2023;210–24.

18. Salvioni L, Morelli L, Ochoa E, Labra M, Fiandra L, Palugan L, Et Al. The Emerging Role Of Nanotechnology In Skincare. Adv Colloid Interface Sci [Internet]. 2021;293:102437. Available From: Https://Doi.Org/10.1016/J.Cis.2021.102437

19. Hutauruk H, Yamlean Pvy, Wiyono W. Formulasi Dan Uji Aktivitas Sabun Cair Ekstrak Etanol Herba Seledri (Apium Graveolens L) Terhadap Bakteri Staphylococcus Aureus. Pharmacon. 2020;9(1):73.

20. Ismail I, Handayany Gn, Wahyuni D. Formulasi Dan Penentuan Nilau Spf ( Sun Protecting Factor) Sediaan Krim Tabir Surya Ekstrak Etanol Daun Kemangi (Ocimum Sanctum L .). Jf Fik Uinam. 2014;2(1):6–11.

21. Tungadi R, Pakaya Ms, Ali Pda. Formulasi Dan Evaluasi Stabilitas Fisik Sediaan Krim Senyawa Astaxanthin. 2023;3(1):117–24.

22. Firdaus S, Utari Au, Alifah Dy, Jumardin W. Penentuan Nilai Spf ( Sun Protection Factor ) Krim Ekstrak Etanol Daun Belimbing Wuluh ( Averrhoa Bilimbi L .) Menggunakan Metode Spektrofotometri. 2024;12(2):67–77.

23. Joen Ja, Fransiska M, Agustini Tt, Sari S. Literature Review : Pemanfaatan Bahan Alam Sebagai Agen Fotoprotektif Dalam Kosmetik Tabir Surya. 2025;9:8879–90.

Unduhan

Diterbitkan

2026-07-19

Cara Mengutip

AKTIVITAS FOTOPROTEKTIF IN VITRO SEDIAAN KRIM EKSTRAK HERBA PUTRI MALU (Mimosa pudica L.) SEBAGAI TABIR SURYA. (2026). Jurnal Farmasi IKIFA, 5(2), 97-114. https://epik.ikifa.ac.id/jfi/article/view/409