LITERATURE STUDY ON ANTIHYPERTENSIVE THERAPY IN PREGNANCY

Bilah Samping Artikel

PDF (English)
Diterbitkan: Okt 31, 2024

Isi Artikel Utama

Junaedi
Politeknik Kesehatan Kemenkes Jakarta II
Nanang Kurnia Achmadi
Poltekkes Kemenkes Jakarta II
Yetri Elisya
Poltekkes Kemenkes Jakarta II
Dwi Yunita Rizki Fajarsari
Poltekkes Kemenkes Jakarta II

Abstrak

Hypertension is one of the leading causes of maternal and fetal mortality and has more serious repercussions during childbirth. The three foremost causes of maternal mortality in obstetrics are hemorrhages (45%), infection (15%), and preeclampsia (13%). In pregnancy, hypertension is referred to as systolic blood pressure above 140 mmHg or diastolic blood pressure higher over 90 mmHg. Due to the risk of teratogenic effects of medication and mother physiologic changes in response to pregnancy, treatment during pregnancy requires special consideration. Methyldopa and Nifedipine are antihypertensive medications that can be performed during pregnancy. Antihypertensive therapy in pregnancy should be determined based on the pregnant patient's age, the class of antihypertensive drugs, single medications, and antihypertensive therapy combinations. As stated by results of this study, more pregnant women had hypertension between the ages of 26 and 30.  When compared to other antihypertensive groups, nifedipine plus calcium blockers (CCB) is the safest and most effective type of antihypertensive therapy for pregnant women. Furthermore, some patients with hypertension in pregnancy require a combination of therapies to meet blood pressure targets; the use of a combination of nifedipine and methyldopa has been shown to overcome hypertension in pregnancy.


 


 

Rincian Artikel

##submission.howToCite##
Junaedi, Nanang Kurnia Achmadi, Yetri Elisya, & Dwi Yunita Rizki Fajarsari. (2024). LITERATURE STUDY ON ANTIHYPERTENSIVE THERAPY IN PREGNANCY. Jurnal Farmasi IKIFA, 3(3), 45-50. Diambil dari https://epik.ikifa.ac.id/index.php/jfi/article/view/213
Terbitan
Vol 3 No 3 (2024): JURNAL FARMASI IKIFA VOL.3 NO.2 OKTOBER TAHUN 2024
Bagian
Articles
##submission.license.cc.by-sa4.footer##

Referensi

1. Chobanian A V., Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension. 2003;42(6):1206–52.
2. Ima Mariama. Gambaran Penatalaksanaan Hipertensi Dalam Kehamilan Dan Faktor
Predisposisi Pada Ny. D G6p3a2 Di Puskesmas Telagasari Kabupaten Karawang Tahun
2020. 0;000(1):2–8.
3. World Health Organization. World Statistics 2015
4. Prabhakara G. Health Statistics (Health Information System). Short Textbook of
Preventive and Social Medicine. 2010. 28–28 p.
5. Maryunani A, Yulianingsih. Asuhan Kegawatdaruratan dalam Kebidanan . Jakarta; 2009.
6. Yesi A. Hipertensi Dalam Kehamilan. BidanKita. 2018. 38 p.
7. Sidani M, Siddik-sayyid SM. Preeclampsia, A New Perspective In 2011 I-Introduction- Definitions. J Anesth. 2011;21(2):2011.
8. Dyah B, Perwitasari A, Goyena R, Ibrahim SS, Bougalambou ASI, Rahmawati F, et al.
Studi Eksplorasi Penatalaksanaan Hipertensi Pada Wanita Hamil. J Chem Inf Model.
2018;1(2):281–5.
9. Mudjari NS, Samsu N. Management of hypertension in pregnancy . 2015 [cited 2022 Jul
26];78–86. Available from: https://pubmed.ncbi.nlm.nih.gov/25948773/
10. Moore BA, Barnett JE. Hypertension in pregnancy. Case Stud Clin Psychol Sci Bridg Gap from Sci to Pract [Internet]. 2015 [cited 2022 Jul 26];(August):1–7. Available from: https://academic.oup.com/book/24370/chapter/187252657
11. Andriana DD, Utami ED, Sholihat NK. Drug Use Evaluation of Antihypertensive in Pre- Eclampsia In-Patients in Dr. Margono Soekarjo General Hospital Purwokerto Period of January 2015-June 2016. Acta Pharm Indones J. 2018;6(1):29–39.
12. Kundarto W, Faizah RN. Evaluasi Terapi Antihipertensi Pada Pasien Preeklampsia Berat di Instalasi Rawat Inap RSUD Dr. Moewardi Periode Januari - Juni Tahun 2017. JPSCR J Pharm Sci Clin Res. 2021;6(2):228.
13. Komalasari NP. Pola peresepan obat antihipertensi pada ibu hamil di rumah sakit ibu dan anak pala raya mejasem. 2019;
14. Kencana Dewi NMR. Pola Pengobatan Antihipertensi pada Pasien Preeklampsia di
Rumah Sakit Harapan Bunda. J Sos Sains. 2021;1(7):637–44.
15. Elly Rakhmawati LBGP. Studi Penggunaan Obat Anti Hipertensi Pada Pasien
Preeklamsia Di Instalasi Rawat Inap RS Aura Syiva Tahun 2018. 2018;2(1)
16. Nur Syamsiyatul Aliyah, Agustin Wjayanti WSM. Evaluasi Penggunaan Obat Anti Hipertensi Pada Pasien Pre eklampsia Dan Eklampsia Di Instalasi Rawat Inap RSUD Panembahan Senopati Bantul Yogyakarta Periode Tahun 2014-2015. 2015;II:1–15.
17. Yulianti W, Permadi YW, Zuhana N, Muthoharoh A. Efektivitas Penggunaan Obat Antihipertensi Pada Preeklampsia Di Instalasi Rawat Inap Rsud Kajen Kabupaten Pekalongan Periode Januari - Desember Tahun 2018. 2018;
18. Dewi NK. Evaluasi Ketepatan Dan Efektivitas Terapi Hipertensi Pada Ibu Hamil Dengan
Preeklampsia/ Eklampsia Di RST dr. Soedjono Kota Magelang Januari 2017-Juni 2018.
2019;
19. Alfalasifah I. Evaluasi Ketepatan Penggunaan Obat Antihipertensi pada Ibu Hamil di


Instalasi Rawat Inap RSUD Pandan Arang Boyolali Periode Januari - September Tahun
2016. 2017;1–18.
20. Babbar K, Armo M, Bhanja R. A comparative study of efficacy of antihypertensive drugs andfeto-maternal outcome in the treatment of pregnancy induced hypertension. Int J Reprod Contraception, Obstet Gynecol. 2015;4(6):1846–52.
21. Prawirohardjo S. Ilmu Kandungan. 2nd ed. Wiknjosastro H, Saifuddin BA, Rachimhadhi
T, editors. 2007.
22. Sukfitrianty, Aswadi, Lagu AMHR. Faktor Risiko Hipertensi Pada Ibu Hamil Di Rumah Sakit Hikmah Kota Makassar. Al-Sihah Public Heal Sci J [Internet]. 2016;8(1):79–88. Available from: http://journal.uin-alauddin.ac.id/index.php/Al-Sihah/article/view/2086
23. Dipiro JT, Wells BG, Schwinghammer TL, Dipiro C V. Pharmacoteraphy Handbook
Seventh Edition. Vol. 7. USA : McGraw-Hill Company; 2008.
24. Ghanem FA, Movahed A, Assad Movahed C. Use of Antihypertensive Drugs during
Pregnancy and Lactation.
25. Alatas H. Hipertensi pada Kehamilan. Herb-Medicine J. 2019;2(2):27.